MCAS · High Histamine · PNI Sevilla

When mast cells activate without a clear cause: a complex condition that requires strategy.

What is MCAS?

The Mast Cell Activation Syndrome is a condition in which mast cells (immune system cells that release histamine and other mediators) activate excessively in response to stimuli that should not trigger them. Symptoms: facial redness, itching, hives, tachycardia, digestive problems, brain fog, fatigue, new multiple intolerances, reactions to odors/heat/temperature changes.

How we approach it

Collaborative work with your allergist, when applicable. Low-histamine + low-histamine-releaser nutritional plan. Targeted supplementation (quercetin, tolerable form of vitamin C, B6, copper). Gut care (dysbiosis worsens MCAS). Stress management (HPA axis highly involved). Patience and consistency — it is a condition that improves slowly.

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